Cancer Informatics

Cancer Informatics PDF
Author: John S. Silva
Publisher: Springer
ISBN: 9781461265474
Size: 80.52 MB
Format: PDF
Category : Medical
Languages : en
Pages : 377
View: 2844

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Cancer Informatics chronicles the development of the National Cancer Institute's new Cancer Informatics Infrastructure (CII) - an information management system infrastructure designed to faciliate clinical trials, provide for reliable, secure information exchange, and improve patient care. The book details the challenges involved in creating and managing such a knowledge base, including technologies, standards, and current, state-of-the-art applications. The ultimate goal of CII is to function as an enabler of clinical trials, expediting the clinical trials lifecycle, faciliating faster and safer drug development and more appropriate treatment choices for cancer patients. Contributors address the role the CII must play in converting the growing knowledge of genes, proteins, and pathways into appropriate preventative, diagnostic, and therapeutic measures. Presented in four sections, the first provides an overview of the processes involved in moving the infrastructure for cancer from theory into practice. Sections two through four offer the latest work done in the areas of technology, cancer-specific and national standards, and applications to faciliate clinical trials.

Cancer Informatics

Cancer Informatics PDF
Author: John S. Silva
Publisher: Springer Science & Business Media
ISBN: 1461300630
Size: 17.70 MB
Format: PDF, ePub
Category : Medical
Languages : en
Pages : 377
View: 2825

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Cancer Informatics chronicles the development of the National Cancer Institute's new Cancer Informatics Infrastructure (CII) - an information management system infrastructure designed to faciliate clinical trials, provide for reliable, secure information exchange, and improve patient care. The book details the challenges involved in creating and managing such a knowledge base, including technologies, standards, and current, state-of-the-art applications. The ultimate goal of CII is to function as an enabler of clinical trials, expediting the clinical trials lifecycle, faciliating faster and safer drug development and more appropriate treatment choices for cancer patients. Contributors address the role the CII must play in converting the growing knowledge of genes, proteins, and pathways into appropriate preventative, diagnostic, and therapeutic measures. Presented in four sections, the first provides an overview of the processes involved in moving the infrastructure for cancer from theory into practice. Sections two through four offer the latest work done in the areas of technology, cancer-specific and national standards, and applications to faciliate clinical trials.

Cancer Informatics In The Post Genomic Era

Cancer Informatics in the Post Genomic Era PDF
Author: Igor Jurisica
Publisher: Springer Science & Business Media
ISBN: 0387693211
Size: 16.83 MB
Format: PDF, ePub
Category : Medical
Languages : en
Pages : 180
View: 2146

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Cancer Informatics in Post-Genomic Era provides both the necessary methodology and practical information tools for analyzing data in the field of medical information science. This, of course, requires analytic tools. Those tools are garnered by developing and assessing methods and systems for the acquisition, processing, and interpretation of patient data, aided by scientific discovery. Key challenges in this field include integrating research and clinical care, sharing data, and establishing partnerships within and across sectors of patient diagnosis and treatment.

Informatics Needs And Challenges In Cancer Research

Informatics Needs and Challenges in Cancer Research PDF
Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309259487
Size: 58.32 MB
Format: PDF, ePub
Category : Medical
Languages : en
Pages : 146
View: 2810

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As information technology becomes an integral part of health care, it is important to collect and analyze data in a way that makes the information understandable and useful. Informatics tools--which help collect, organize, and analyze data--are essential to biomedical and health research and development. The field of cancer research is facing an overwhelming deluge of data, heightening the national urgency to find solutions to support and sustain the cancer informatics ecosystem. There is a particular need to integrate research and clinical data to facilitate personalized medicine approaches to cancer prevention and treatment--for example, tailoring treatment based on an individual patient's genetic makeup as well as that of the tumor --and to allow for more rapid learning from patient experiences. To further examine informatics needs and challenges for 21st century biomedical research, the IOM's National Cancer Policy Forum held a workshop February 27-28, 2012. The workshop was designed to raise awareness of the critical and urgent importance of the challenges, gaps and opportunities in informatics; to frame the issues surrounding the development of an integrated system of cancer informatics for acceleration of research; and to discuss solutions for transformation of the cancer informatics enterprise. Informatics Needs and Challenges in Cancer Research: Workshop Summary summarizes the workshop.

Cancer Informatics

Cancer Informatics PDF
Author:
Publisher:
ISBN:
Size: 58.44 MB
Format: PDF, Docs
Category :
Languages : en
Pages :
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Informatics Needs And Challenges In Cancer Research

Informatics Needs and Challenges in Cancer Research PDF
Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309259517
Size: 47.18 MB
Format: PDF, ePub
Category : Medical
Languages : en
Pages : 146
View: 721

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As information technology becomes an integral part of health care, it is important to collect and analyze data in a way that makes the information understandable and useful. Informatics tools--which help collect, organize, and analyze data--are essential to biomedical and health research and development. The field of cancer research is facing an overwhelming deluge of data, heightening the national urgency to find solutions to support and sustain the cancer informatics ecosystem. There is a particular need to integrate research and clinical data to facilitate personalized medicine approaches to cancer prevention and treatment--for example, tailoring treatment based on an individual patient's genetic makeup as well as that of the tumor --and to allow for more rapid learning from patient experiences. To further examine informatics needs and challenges for 21st century biomedical research, the IOM's National Cancer Policy Forum held a workshop February 27-28, 2012. The workshop was designed to raise awareness of the critical and urgent importance of the challenges, gaps and opportunities in informatics; to frame the issues surrounding the development of an integrated system of cancer informatics for acceleration of research; and to discuss solutions for transformation of the cancer informatics enterprise. Informatics Needs and Challenges in Cancer Research: Workshop Summary summarizes the workshop.

Biomedical Informatics For Cancer Research

Biomedical Informatics for Cancer Research PDF
Author: Michael F. Ochs
Publisher: Springer Science & Business Media
ISBN: 1441957146
Size: 19.63 MB
Format: PDF, Mobi
Category : Medical
Languages : en
Pages : 354
View: 6314

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view, showing that multiple molecular pathways must be affected for cancer to develop, but with different specific proteins in each pathway mutated or differentially expressed in a given tumor (The Cancer Genome Atlas Research Network 2008; Parsons et al. 2008). Different studies demonstrated that while widespread mutations exist in cancer, not all mutations drive cancer development (Lin et al. 2007). This suggests a need to target only a deleterious subset of aberrant proteins, since any tre- ment must aim to improve health to justify its potential side effects. Treatment for cancer must become highly individualized, focusing on the specific aberrant driver proteins in an individual. This drives a need for informatics in cancer far beyond the need in other diseases. For instance, routine treatment with statins has become widespread for minimizing heart disease, with most patients responding to standard doses (Wilt et al. 2004). In contrast, standard treatment for cancer must become tailored to the molecular phenotype of an individual tumor, with each patient receiving a different combination of therapeutics aimed at the specific aberrant proteins driving the cancer. Tracking the aberrations that drive cancers, identifying biomarkers unique to each individual for molecular-level di- nosis and treatment response, monitoring adverse events and complex dosing schedules, and providing annotated molecular data for ongoing research to improve treatments comprise a major biomedical informatics need.

2018 1st International Conference On Cancer Care Informatics Cci

2018 1st International Conference on Cancer Care Informatics  CCI  PDF
Author: IEEE Staff
Publisher:
ISBN: 9781728114484
Size: 80.80 MB
Format: PDF, Docs
Category :
Languages : en
Pages :
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CancerCareInformatics is the first international conference on Cancer Informatics attracting researchers, policy makers, and practitioners that employ informatics to empower cancer care holistically, where the cancer patient is the focus in the cancer care journey involving all concerned stakeholders The conference is aimed at attracting state of the art research in the provision of (1) cancer care software services, clouds and tools, (2) big data analytics for cancer care, (3) reducing the digital divide in cancer care, (4) Cancer Care and Life Long Learning, (5) Legal, Social, Ethical and Professional Issues in Cancer Care Informatics, (6) methods for evaluating the effectiveness of employing cancer care informatics strategies, policies, etc

Statistics And Informatics In Molecular Cancer Research

Statistics and Informatics in Molecular Cancer Research PDF
Author: Carsten Wiuf
Publisher: Oxford University Press
ISBN: 0199532877
Size: 48.36 MB
Format: PDF, Docs
Category : Mathematics
Languages : en
Pages : 196
View: 1606

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Molecular understanding of cancer and cancer progression is at the forefront of many research programs today, and high-throughput array technologies and other modern molecular techniques produce a wealth of molecular data about the structure, organization, and function of cells, tissues and organisms. Many experimental researchers are not familiar with the tools and techniques applied for the analysis of the data, and statisticians are rarely familiar with thebiological background. This book aims at bridging the gap between the two; in eight chapters, edited by two leading researchers with contributions from carefully chosen experts, novel advances instatistics and informatics are explained for a general audience and how the tools are useful for gaining new and useful information about cancer as a complex disease.

Informatics In Radiation Oncology

Informatics in Radiation Oncology PDF
Author: George Starkschall
Publisher: CRC Press
ISBN: 1439825831
Size: 64.55 MB
Format: PDF, Kindle
Category : Science
Languages : en
Pages : 329
View: 993

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Reflecting the increased importance of the collaborations between radiation oncology and informatics professionals, Informatics in Radiation Oncology discusses the benefits of applying informatics principles to the processes within radiotherapy. It explores how treatment and imaging information is represented, stored, and retrieved as well as how this information relates to other patient data. The book deepens your knowledge of current and emerging information technology and informatics principles applied to radiation oncology so that all the data gathered—from laboratory results to medical images—can be fully exploited to make treatments more effective and processes more efficient. After introducing the basics of informatics and its connection to radiation oncology, the book examines the process of healthcare delivery in radiation oncology, the challenges of managing images in radiotherapy, and the burgeoning field of radiogenomics. It then presents teaching, clinical trials, and research tools and describes open access clinical imaging archives in radiotherapy, techniques for maximizing information from multimodality imaging, and the roles of images in treatment planning. It also looks at how informatics can improve treatment planning, the safety and efficiency of delivery systems, image-guided patient positioning, and patient assessment. The book concludes with discussions on how outcomes modeling evaluates the effectiveness of treatments, how quality control informatics improves the reliability of processes, and how to perform quality assurance on the informatics tools. With contributions from a host of top international experts in radiation oncology, medical physics, and informatics, this book leads the way in moving the field forward. It encourages you to find new ways of applying informatics to radiation oncology and help your patients in their fight against cancer.