Molecular Pathology Of Pituitary Adenomas

Molecular Pathology of Pituitary Adenomas PDF
Author: Cristiana Tanase
Publisher: Elsevier
ISBN: 0124158528
Size: 61.15 MB
Format: PDF, Mobi
Category : Medical
Languages : en
Pages : 130
View: 6310

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The pituitary gland is an important one since it controls several of the other hormone glands, such as the thyroid and adrenals. A pituitary adenoma is an abnormal growth or tumor in this gland, and they are the subject of very active clinical and pathological research. This book examines the latest developments in this field and discusses the most important molecules implicated in apoptosis, angiogenesis and signal transduction. A good understanding of these processes is needed to identify the best therapies. Facilitates the understanding of the processes involved and how they are translated into therapy Illustrations are used to explain the complex mechanisms involved

The Pituitary Adenoma

The Pituitary Adenoma PDF
Author: Kalmon D. Post
Publisher: Springer Science & Business Media
ISBN: 1468436686
Size: 62.96 MB
Format: PDF, Kindle
Category : Medical
Languages : un
Pages : 507
View: 3091

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The idea for this book developed as an outcome of a multidisciplinary sym posium entitled "Pituitary Adenoma Update" that was held at Tufts-New En gland Medical Center in April 1977. The purpose of that symposium was to put together our current knowledge of the cause of pituitary tumors and discuss the diagnostic evaluation and management that was now appropriate, in light of the rapid advances that had taken place so recently in this area. Those of our colleagues who had presented papers at the symposium, as well as a number of others, were invited to contribute to this volume, which should serve as a presentation of the "state of the art" on all aspects of pitu itary tumors. We felt that such a book would be of value to endocrinologists, neurosurgeons, neuroradiologists, and pathologists who are involved in the investigation or care of patients with pituitary disorders. For a number of reasons, a review of pituitary adenomas seems particu larly timely. Rapid advances have taken place coincidentally in the fields of neurosurgery, neuroendocrinology, neuroradiology, neuropathology, and neuropharmacology. Seven major developments in these areas have occurred independently and almost simultaneously that have virtually revolutionized our approach to pituitary adenomas.

Molecular Pathology Of Pituitary Adenomas

Molecular Pathology of Pituitary Adenomas PDF
Author: Cristiana Tanase
Publisher: Elsevier
ISBN: 0124158307
Size: 24.53 MB
Format: PDF
Category : Medical
Languages : un
Pages : 113
View: 3999

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The pituitary gland is an important one since it controls several of the other hormone glands, such as the thyroid and adrenals. A pituitary adenoma is an abnormal growth or tumor in this gland, and they are the subject of very active clinical and pathological research. This book examines the latest developments in this field and discusses the most important molecules implicated in apoptosis, angiogenesis and signal transduction. A good understanding of these processes is needed to identify the best therapies. Facilitates the understanding of the processes involved and how they are translated into therapy Illustrations are used to explain the complex mechanisms involved

Pituitary Adenomas

Pituitary Adenomas PDF
Author: Alex M. Landolt
Publisher: W.B. Saunders Company
ISBN:
Size: 51.26 MB
Format: PDF, ePub, Docs
Category : Medical
Languages : en
Pages : 540
View: 6703

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This text on pituitary adenomas is divided into three sections, covering their biology and pathology, clinical findings and diagnosis, and their treatment.

Treatment Of Pituitary Adenomas

Treatment of Pituitary Adenomas PDF
Author: Rudolf Fahlbusch
Publisher:
ISBN: 9783135538013
Size: 24.73 MB
Format: PDF
Category : Hypophyse - Tumeurs - Congrès
Languages : en
Pages : 445
View: 3172

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Modern Neurosurgery Of Meningiomas And Pituitary Adenomas

Modern Neurosurgery of Meningiomas and Pituitary Adenomas PDF
Author: R. Fahlbusch
Publisher: Springer Science & Business Media
ISBN: 3709194504
Size: 40.96 MB
Format: PDF
Category : Medical
Languages : un
Pages : 112
View: 2706

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"Modem Neurosurgery of Meningiomas and Pituitary Adenomas" presents the state-of-the-art of neurosurgery for these two types of tumors. Following a classification of the pituitary adenomas according to pathology, molecular biological factors are presented and their effects evaluated as these aspects deepen our understanding of the growth and further expansion of these tumors. The diagnosis is made not only by a study of the hormonal status, but also by neuroradiology. A number of authors have devoted their efforts to the special problem groups such as the elderly patients and those with huge pituitary adenomas. Particular emphasis is of course placed on the surgical treatment, including transcranial and transphenoidal neurosurgery, but the use of medical treatment and irradiation must be discussed as well. The treatment of meningiomas has also been influenced by the molecular biology of hormone and growth factors. Therefore it is accorded extensive space in this volume. The prognostic significance of nuclear DNA content is discussed. Recent research with new diagnostic methods such as somatostatin scintigraphy, PET studies end progesterone receptor in tumor fragment spheroids is presented here. The treatment of these tumors, however, depends largely on their localization. For the neurosurgeon, the surgical treatment of meningiomas involving the cavernous sinus, meningiomas of the ventral Foramen of Monroe, meningiomas of the cerebello pontine angle and of the optic sheath is presented by prominent experienced leaders in this field.

Diagnosis And Management Of Pituitary Tumors

Diagnosis and Management of Pituitary Tumors PDF
Author: Kamal Thapar
Publisher: Springer Science & Business Media
ISBN: 1592592171
Size: 56.29 MB
Format: PDF, Mobi
Category : Medical
Languages : en
Pages : 496
View: 478

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Eminent clinicians and specialists thoroughly review in great detail every aspect of pituitary tumors. The topics covered include prolactinomas, somatotroph adenomas, corticotroph adenomas, thyrotroph adenomas, nonfunctioning tumors, pituitary tumors, invasive adenomas, and pituitary carcinomas, as well as lesions, exclusive of pituitary adenomas, that occur in the sellar region. Also discussed are the new methods in endocrine diagnosis, high resolution imaging, receptor-mediated pharmacotherapy, microsurgical techniques, improved methods of radiation delivery, and the development of a precise and physiologically meaningful classification of pituitary tumors. Much-needed and brilliantly multidisciplinary, Diagnosis and Management of Pituitary Tumors offers all those dealing with pituitary cancer patients today's most comprehensive guide to diagnosis and treatment, one whose coordinated treatment strategies have sharply improved long-term survival rates for many patients.

The Pituitary

The Pituitary PDF
Author: Shlomo Melmed
Publisher: Academic Press
ISBN: 9780123809278
Size: 59.23 MB
Format: PDF, Kindle
Category : Medical
Languages : en
Pages : 744
View: 4630

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The pituitary, albeit a small gland, is known as the "master gland" of the endocrine system and contributes to a wide spectrum of disorders, diseases, and syndromes. Since the publication of the second edition of The Pituitary, in 2002, there have been major advances in the molecular biology research of pituitary hormone production and action and there is now a better understanding of the pathogenesis of pituitary tumors and clinical syndromes resulting in perturbation of pituitary function. There have also been major advances in the clinical management of pituitary disorders. Medical researchers and practitioners now better understand the morbidity and mortality associated with pituitary hormone hyposecretion and hypersecretion. Newly developed drugs, and improved methods of delivering established drugs, are allowing better medical management of acromegaly and prolactinoma. These developments have improved the worldwide consensus around the definition of a "cure" for pituitary disease, especially hormone hypersecretion, and hence will improve the success or lack of success of various forms of therapy. It is therefore time for a new edition of The Pituitary. The third edition will continue to be divided into sections that summarize normal hypothalamic-pituitary development and function, hypothalamic-pituitary failure, and pituitary tumors; additional sections will describe pituitary disease in systemic disorders and diagnostic procedures, including imaging, assessment of the eyes, and biochemical testing. The first chapter will be completely new – placing a much greater emphasis on physiology and pathogenesis. Two new chapters will be added on the Radiation and Non-surgical Management of the Pituitary and Other Pituitary Lesions. Other chapters will be completely updated and many new author teams will be invited. The second edition published in 2002 and there have been incredible changes in both the research and clinical aspects of the pituitary over the past 8 years – from new advances in growth hormones to pituitary tumor therapy. Presents a comprehensive, translational source of information about the pituitary in one reference work Pituitary experts (from all areas of research and practice) take readers from the bench research (cellular and molecular mechanism), through genomic and proteomic analysis, all the way to clinical analysis (histopathology and imaging) and new therapeutic approaches Clear presentation by endocrine researchers of the cellular and molecular mechanisms underlying pituitary hormones and growth factors as well as new techniques used in detecting lesions (within the organ) and other systemic disorders Clear presentation by endocrinologists and neuroendocrine surgeons of how imaging, assessment of the eyes, and biochemical testing can lead to new therapeutic approaches