The Epigenetics Revolution

The Epigenetics Revolution PDF
Author: Nessa Carey
Publisher: Columbia University Press
ISBN: 0231530714
Size: 31.15 MB
Format: PDF, ePub, Docs
Category : Science
Languages : en
Pages : 352
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Epigenetics can potentially revolutionize our understanding of the structure and behavior of biological life on Earth. It explains why mapping an organism's genetic code is not enough to determine how it develops or acts and shows how nurture combines with nature to engineer biological diversity. Surveying the twenty-year history of the field while also highlighting its latest findings and innovations, this volume provides a readily understandable introduction to the foundations of epigenetics. Nessa Carey, a leading epigenetics researcher, connects the field's arguments to such diverse phenomena as how ants and queen bees control their colonies; why tortoiseshell cats are always female; why some plants need cold weather before they can flower; and how our bodies age and develop disease. Reaching beyond biology, epigenetics now informs work on drug addiction, the long-term effects of famine, and the physical and psychological consequences of childhood trauma. Carey concludes with a discussion of the future directions for this research and its ability to improve human health and well-being.

Hacking The Code Of Life

Hacking the Code of Life PDF
Author: Nessa Carey
Publisher: Icon Books
ISBN: 1785784986
Size: 46.31 MB
Format: PDF, Docs
Category : Science
Languages : en
Pages : 176
View: 1941

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'[A]n excellent, brisk guide to what is likely to happen as opposed to the fantastically remote.' - Los Angeles Review of Books In 2018 the world woke up to gene editing with a storm of controversy over twin girls born in China with genetic changes deliberately introduced by scientists – changes they will pass on to their own offspring. Genetic modification (GM) has been with us for 45 years now, but the new system known as CRISPR or gene editing can manipulate the genes of almost any organism with a degree of precision, ease and speed that we could only dream of ten years ago. But is it ethical to change the genetic material of organisms in a way that might be passed on to future generations? If a person is suffering from a lethal genetic disease, is it unethical to deny them this option? Who controls the application of this technology, when it makes ‘biohacking’ – perhaps of one’s own genome – a real possibility? Nessa Carey’s book is a thrilling and timely snapshot of a cutting-edge technology that will radically alter our futures and the way we prevent disease. 'A focused snapshot of a brave new world.' - Nature 'A brisk, accessible primer on the fast-moving field, a clear-eyed look at a technology that is already driving major scientific advances - and raising complex ethical questions.' - Emily Anthes, Undark

Epigenetics And Human Reproduction

Epigenetics and Human Reproduction PDF
Author: Sophie Rousseaux
Publisher: Springer Science & Business Media
ISBN: 9783642147739
Size: 45.98 MB
Format: PDF, Kindle
Category : Medical
Languages : en
Pages : 372
View: 182

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Epigenetics is a rapidly expanding field in medical and biological research which concerns heritable traits that are not attributable to changes in the DNA sequence. Epigenetic mechanisms play key roles in many biological processes, and it has become clear that their disruption can gives rise to diverse pathologies in humans. Edited by preeminent experts, Sophie Rousseaux and Saadi Khochbin, this volume in the ‘Epigenetics and Human Health’ series discusses the role of epigenetics in human reproduction

Reliability Assessments

Reliability Assessments PDF
Author: Franklin Richard Nash, Ph.D.
Publisher: CRC Press
ISBN: 1315353849
Size: 80.61 MB
Format: PDF, ePub, Docs
Category : Business & Economics
Languages : en
Pages : 784
View: 1163

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This book provides engineers and scientists with a single source introduction to the concepts, models, and case studies for making credible reliability assessments. It satisfies the need for thorough discussions of several fundamental subjects. Section I contains a comprehensive overview of assessing and assuring reliability that is followed by discussions of: • Concept of randomness and its relationship to chaos • Uses and limitations of the binomial and Poisson distributions • Relationship of the chi-square method and Poisson curves • Derivations and applications of the exponential, Weibull, and lognormal models • Examination of the human mortality bathtub curve as a template for components Section II introduces the case study modeling of failure data and is followed by analyses of: • 5 sets of ideal Weibull, lognormal, and normal failure data • 83 sets of actual (real) failure data The intent of the modeling was to find the best descriptions of the failures using statistical life models, principally the Weibull, lognormal, and normal models, for characterizing the failure probability distributions of the times-, cycles-, and miles-to-failure during laboratory or field testing. The statistical model providing the preferred characterization was determined empirically by choosing the two-parameter model that gave the best straight-line fit in the failure probability plots using a combination of visual inspection and three statistical goodness-of-fit (GoF) tests. This book offers practical insight in dealing with single item reliability and illustrates the use of reliability methods to solve industry problems.

Biofictions

Biofictions PDF
Author: Josie Gill
Publisher: Bloomsbury Publishing
ISBN: 1350099848
Size: 33.25 MB
Format: PDF, ePub, Mobi
Category : Literary Criticism
Languages : en
Pages : 208
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In this important interdisciplinary study, Josie Gill explores how the contemporary novel has drawn upon, and intervened in, debates about race in late 20th and 21st century genetic science. Reading works by leading contemporary writers including Zadie Smith, Kazuo Ishiguro, Octavia Butler and Colson Whitehead, Biofictions demonstrates how ideas of race are produced at the intersection of science and fiction, which together create the stories about identity, racism, ancestry and kinship which characterize our understanding of race today. By highlighting the role of narrative in the formation of racial ideas in science, this book calls into question the apparent anti-racism of contemporary genetics, which functions narratively, rather than factually or objectively, within the racialized contexts in which it is embedded. In so doing, Biofictions compels us to rethink the long-asked question of whether race is a biological fact or a fiction, calling instead for a new understanding of the relationship between race, science and fiction.

The Solar Revolution

The Solar Revolution PDF
Author: Steve McKevitt
Publisher: Icon Books Ltd
ISBN: 1848317875
Size: 32.60 MB
Format: PDF, Kindle
Category : Technology & Engineering
Languages : en
Pages : 320
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It’s an astonishing fact that capturing all the energy in just one hour’s worth of sunlight would enable us to meet the planet’s food and energy needs for an entire year. The Solar Revolution tells the story of how scientists are working to reconnect us to the ‘solar economy’, harnessing the power of the sun to provide sustainable food and energy for a global population of 10 billion people: an achievement that would end our dependence on ‘fossilised sunshine’ in the form of coal, oil and gas and remake our connection with the soil that grows our food. Steve McKevitt and Tony Ryan describe the human race’s complex relationship with the sun and take us back through history to see how our world became the place it is today – chemically, geologically, ecologically, climatically and economically – before moving on to the cutting-edge science and technology that will enable us to live happily in a sustainable future.

Altruism

Altruism PDF
Author: Matthieu Ricard
Publisher: Hachette UK
ISBN: 0316208213
Size: 67.75 MB
Format: PDF, ePub
Category : Self-Help
Languages : en
Pages : 864
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The author of the international bestseller Happiness makes a passionate case for altruism -- and why we need it now more than ever. In Happiness, Matthieu Ricard demonstrated that true happiness is not tied to fleeting moments or sensations, but is an enduring state of soul rooted in mindfulness and compassion for others. Now he turns his lens from the personal to the global, with a rousing argument that altruism -- genuine concern for the well-being of others -- could be the saving grace of the 21st century. It is, he believes, the vital thread that can answer the main challenges of our time: the economy in the short term, life satisfaction in the mid-term, and environment in the long term. Ricard's message has been taken up by major economists and thinkers, including Dennis Snower, Amartya Sen, Joseph Stiglitz, and George Soros. Matthieu Ricard makes a robust and passionate case for cultivating altruistic love and compassion as the best means for simultaneously benefitting ourselves and our society. It's a fresh outlook on an ardent struggle -- and one that just might make the world a better place.

Feeling Good

Feeling Good PDF
Author: C. Robert Cloninger M.D.
Publisher: Oxford University Press
ISBN: 9780198021841
Size: 43.19 MB
Format: PDF
Category : Medical
Languages : en
Pages : 400
View: 7529

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All human beings have spontaneous needs for happiness, self-understanding, and love. In Feeling Good: The Science of Well Being, psychiatrist Robert Cloninger describes a way to coherent living that satisfies these strong basic needs through growth in the uniquely human gift of self-awareness. The scientific findings that led Dr. Cloninger to expand his own views in a stepwise manner during 30 years of research and clinical experience are clearly presented so that readers can consider the validity of his viewpoint for themselves. The principles of well-being are based on a non-reductive scientific paradigm that integrates findings from all the biomedical and psychosocial sciences. Reliable methods are described for measuring human thought and social relationships at each step along the path of self-aware consciousness. Practical mental exercises for stimulating the growth of self-awareness are also provided. The methods are supported by data from brain imaging, genetics of personality, and longitudinal biopsychosocial studies. Feeling Good: The Science of Well-Being will be of value to anyone involved in the sciences of the mind or the treatment of mental disorders. It will also interest theologians, philosophers, social scientists, and lay readers because it provides contemporary scientific concepts and language for addressing the perennial human questions about being, knowledge, and conduct.

Vitamania

Vitamania PDF
Author: Catherine Price
Publisher: Penguin
ISBN: 0698192214
Size: 11.58 MB
Format: PDF, Docs
Category : Health & Fitness
Languages : en
Pages : 336
View: 3593

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"A hidden, many-faceted, and urgent story." --Booklist, *STARRED* Most of us know nothing about vitamins. What’s more, what we think we know is harming both our personal nutrition and our national health. By focusing on vitamins at the expense of everything else, we’ve become blind to the bigger picture: despite our belief that vitamins are an absolute good—and the more of them, the better—vitamins are actually small and surprisingly mysterious pieces of a much larger nutritional puzzle. In Vitamania, award-winning journalist Catherine Price offers a lucid and lively journey through our cherished yet misguided beliefs about vitamins, and reveals a straightforward, blessedly anxiety-free path to enjoyable eating and good health. When vitamins were discovered a mere century ago, they changed the destiny of the human species by preventing and curing many terrifying diseases. Yet it wasn’t long before vitamins spread from labs of scientists into the realm of food marketers and began to take on a life of their own. By the end of the Second World War, vitamins were available in forms never before seen in nature—vitamin gum, vitamin doughnuts, even vitamin beer—and their success showed food manufacturers that adding synthetic vitamins to otherwise nutritionally empty products could convince consumers that they were healthy. The era of “vitamania,” as one 1940s journalist called it, had begun. Though we’ve gained much from our embrace of vitamins, what we’ve lost is a crucial sense of perspective. Vitamins may be essential to our lives, but they are not the only important substances in food. By buying into a century of hype and advertising, we have accepted the false idea that particular dietary chemicals can be used as shortcuts to health—whether they be antioxidants or omega-3s or, yes, vitamins. And it’s our vitamin-inspired desire for effortless shortcuts that created today’s dietary supplement industry, a veritable Wild West of overpromising “miracle” substances that can be legally sold without any proof that they are effective or safe. For the countless individuals seeking to maximize their health and who consider vitamins to be the keys to well-being, Price’s Vitamania will be a game-changing look into the roots of America’s ongoing nutritional confusion. Her travels to vitamin manufacturers and food laboratories and military testing kitchens—along with her deep dive into the history of nutritional science— provide a witty and dynamic narrative arc that binds Vitamania together. The result is a page-turning exploration of the history, science, hype, and future of nutrition. And her ultimate message is both inspiring and straightforward: given all that we don’t know about vitamins and nutrition, the best way to decide what to eat is to stop obsessing and simply embrace this uncertainty head-on. By exposing our extraordinary psychological rela¬tionship with vitamins and challenging us to question our beliefs, Vitamania won’t just change the way we think about vitamins. It will change the way we think about food.